A Light‐Triggered Synthetic Nanopore for Controlling Molecular Transport Across Biological Membranes

Controlling biological molecular processes with light is of high interest in research and biomedicine, as allows precise selective activation a non-invasive non-toxic manner. A process benefitting from control the transport cargo across membranes, which conventionally achieved by membrane-puncturing barrel-shaped nanopores. Yet, there considerable to construct more complex gated pores. Here, we pioneer synthetic light-gated nanostructure controls membranes via controllable lid. The light-triggered nanopore self-assembled six pore DNA strands lid strand carrying light-switchable azobenzene molecules. Exposure opens allow small-molecule membranes. Our advances biomimetic chemistry nanotechnology may be used biotechnology, biosensing, targeted drug release, or cells.